Gwynneville is an unincorporated community in Hanover Township, Shelby County, in the U.S. state of Indiana.Gwynneville was platted in 1881, and named after O'Brien Gynne, a local businessman and landowner. A post office opened at Gwynneville in 1881. Gwynneville had its own high school until the school was discontinued around 1918.Gwynneville is located at 39°39′39″N 85°38′53″W / 39.66083°N 85.64806°W / 39.66083; -85.64806.